Department 160
IPM RAS / Structure / Research departments / Department 160 / Projects / THz spectroscopy application

Application of nonstationary THz spectroscopy

Medicine and biology

Exhaled breath analysis

Together with department of Radiation therapy of Nizhny Novgorod Oncology Hospital, we have carried out measurements of NO concentration dynamics in the exhaled breath of oncological patients before/after radiation therapy. The studies have demonstrated an increase of NO concentration (in 2-3 times) in exhaled breath of lung cancer patients after a session of radiation therapy.

Calculated values of Nv for 3 patients before and after radiation therapy
Nv (before RT), % volNv (after RT), % vol
Patient #1 0.018 0.075
Patient #2 0.015 0.034
Patient #3 0.012 0.022
NO absorption lines (f = 150.176 GHz): red line — oncopatient before radiotherapy, blue line — oncopatient after radiotherapy.

THz spectroscopy of biomolecules

High-precise spectroscopy with application of microwave resonators is employed for studying a spectrum of DNA (in solutions with water).

Fragment of spectra (x axis — frequency, GHz): red curve — water, green curve — DNA in big concentration, blue curve — DNA in small concentration.

Security systems

Registration of vapours, evaporated from a surface during natural decomposition, is a promising way for remote detection of explosives. The THz nonstationary spectrometer has been employed for studying explosives vapours compositions.

Substance

Gases, found in explosives vapors

TNT

NO, N2O, NO3, NH3, acetone, CO, CH, CH2

RDX

NO, N2O, CH, CH2, acetone

NG

NO, NH3, CH, CH2

Hi-tech systems

The investigations of semiconductor coatings growth during epitaxy processes are necessary to understand an influence of deposition conditions on the properties of obtained films. Application of THz gas spectroscopy methods allows monitoring the deposition process (in real time!) in gas phase and plasma.

Substance

Frequency, (MHz)

Substance

Frequency, (MHz)

Substance

Frequency, (MHz)

CH2

68380.9

C2H2O

60615.9

CH3OH

76509.7


69007.8


60617.3

CHOOCH3

72684.1


70678.6


60625.7

CH3OCH3

73465.5


70679.5

CH3CHO

76866.4


73468.7


70680.7


76878.9


73472.6

CH2O

72409.3


79099.2

C3H

76199.2


72838.1


79150.1


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